TTK/PLK1-IN-1 (Formula I) is an inhibitor of threonine tyrosine kinase (TTK) and polo-like kinase 1 (PLK1), with IC50 values of 7 nM and 72 nM, respectively. It regulates the spindle assembly checkpoint (SAC) and exhibits antitumor activity against triple-negative breast cancer (TNBC).
Molecular Weight:
523.63
Purity:
97.39%
CAS Number:
[1817791-70-0]
Formula:
C30H33N7O2
Target:
Tyrosine Kinases|||PLK|||Kinesin
T203064
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