O-Desmethylcarvedilol, CAS [[72956-44-6]] Preis auf Anfrage

Product Overview

• Article Name: O-Desmethylcarvedilol, CAS [[72956-44-6]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T203083
• Supplier Catalog Number: T203083
• Alternative Catalog Number: TGM-T203083-10MG,TGM-T203083-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: Desmethylcarvedilol , BM-14242

Product Description

O-Desmethylcarvedilol (Desmethylcarvedilol) is an active metabolite of Carvedilol, a non-selective beta-adrenergic receptor (beta-AR) antagonist. This compound inhibits store overload-induced calcium release in HEK293 cells expressing the RyR2 R4496C mutation (IC50= 7.62 µM). Additionally, O-Desmethylcarvedilol slows the increase in heart rate and prevents diastolic pressure reduction induced by Isoproterenol in conscious rabbits (ED50s = 32 and 5 µg/kg).

Product Properties

• Molecular Weight: 392.45
• CAS Number: [72956-44-6]
• Formula: C23H24N2O4
• Target: Calcium Channel

Images

T203083