(E/Z)-Droloxifene, CAS [[165813-01-4]] Preis auf Anfrage

Product Overview

• Article Name: (E/Z)-Droloxifene, CAS [[165813-01-4]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T203143
• Supplier Catalog Number: T203143
• Alternative Catalog Number: TGM-T203143-10MG,TGM-T203143-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien
• Alternative Names: (E/Z)-3-Hydroxytamoxifen

Product Description

(E/Z)-Droloxifene is a mixture comprising (E)-Droloxifene, known as a selective estrogen receptor modulator, and (Z)-Droloxifene. (E)-Droloxifene binds to estrogen receptors (ER) in rabbit uterine homogenate with an IC50 of 24 nM. It increases uterine weight in immature rats and reduces the uterine weight increase caused by estradiol in juvenile rats. Additionally, (E)-Droloxifene inhibits the growth of human breast cancer cells MCF-7, ZR-75-1, and T47D stimulated by 17beta-estradiol. In contrast, (Z)-Droloxifene shows weak binding to ER and exhibits neither estrogenic nor anti-estrogenic activity.

Product Properties

• Molecular Weight: 387.51
• CAS Number: [165813-01-4]
• Formula: C26H29NO2
• Target: Apoptosis|||Estrogen Receptor/ERR

Images

T203143