PARL-IN-2 (Compound 14) is a covalent inhibitor of the mitochondrial inner membrane protease PARL, with an EC50 value of 0.16 µM. It strongly activates the PINK1/Parkin pathway and enhances PINK1/Parkin-dependent mitophagy.
Molecular Weight:
365.42
Formula:
C22H23NO4
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