JBJ-07-149 is an inhibitor of EGFRL858R/T790M with an IC50 of 1.1 nM. It suppresses the proliferation of Ba/F3 cells with IC50 values of 4.9 µM when used alone, and 0.148 µM when combined with Cetuximab. Additionally, JBJ-07-149 can serve as a target protein ligand for synthesizing [DDC-01-163].
Molecular Weight:
510.61
CAS Number:
[2140807-58-3]
Formula:
C28H26N6O2S
Target:
EGFR
T203265
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