SBI-183 is an orally active QSOX1 inhibitor (Kd: 20 µM). It can inhibit the proliferation and invasion phenotypes of renal carcinoma cell lines, triple-negative breast cancer cell lines, lung adenocarcinoma cell lines, and pancreatic ductal adenocarcinoma. In vivo, SBI-183 suppresses tumor growth in two human renal cell carcinoma xenograft mouse models.
Molecular Weight:
296.36
CAS Number:
[625403-59-0]
Formula:
C18H20N2O2
Target:
Others
T203429
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