FerroLOXIN-1 is a potent inhibitor of 15LOX-2, selectively blocking the production of ferroptosis-promoting HOO-ETE-PE and preventing RSL3-induced ferroptosis (ferroptosis). It interacts closely and specifically with 15LOX-2, particularly engaging with Y154, N155, and W158.
Molecular Weight:
429.39
CAS Number:
[2773428-48-9]
Formula:
C23H16F5N3
Target:
Ferroptosis|||Lipoxygenase
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