STAT3-IN-38, CAS [[3033049-16-7]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T203450
Supplier Catalog Number:
T203450
Alternative Catalog Number:
TGM-T203450-10MG, TGM-T203450-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
STAT3-IN-38 (Compound 4m) is a STAT3 inhibitor with a dissociation constant (K_D) of 45.33 µM for rhSTAT3, and is a derivative of Celastrol. It binds to the SH2 domain of the STAT3 protein, inhibiting phosphorylation at the pTyr705 site and suppressing downstream gene expression of Survivin and Mcl-1. STAT3-IN-38 can arrest the cell cycle and induce apoptosis in colorectal cancer cells.
Molecular Weight:
559.8
CAS Number:
[3033049-16-7]
Formula:
C35H45NO3S
Target:
Apoptosis|||Survivin|||STAT
T203450
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