ANO1-IN-4 (Compound 10bm) is a reversible inhibitor of the calcium-activated chloride channel transmembrane protein 16A (TMEM16A, also known as ANO1), with an IC50 of 0.030 µM. It demonstrates good metabolic stability in rat liver microsomes and can inhibit spontaneous contractions in isolated mouse ileum.
Molecular Weight:
457.33
CAS Number:
[2098490-06-1]
Formula:
C19H19BrF2N2O2S
Target:
Chloride channel
T203487
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