SPA107 (Hemiasterlin methyl ester) is an analogue of Hemiasterlin. It inhibits tubulin polymerization, exhibiting antimitotic activity with an IC50 of 0.5 nM. SPA107 also shows cytotoxicity against p53 mutated MCF-7 cells, with an IC50 of 0.5 nM.
Molecular Weight:
540.74
CAS Number:
[179939-69-6]
Formula:
C31H48N4O4
Target:
Others|||Microtubule Associated
T203520
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