TGR5 agonist 7 (Compound 22-Na) is an intestine-restricted, orally active agonist of the G protein-coupled bile acid receptor TGR5 (GPBAR1 or GPR131) with an EC50 of less than 1 µM. In mouse models, it demonstrates blood glucose-lowering effects, making it useful for diabetes research.
Molecular Weight:
730.93
Formula:
C37H59N2NaO9S
Target:
Others|||GPCR19
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