PPARgamma agonist15 (Compound 7c) functions as an agonist of PPARgamma, inhibiting the expression of alpha-amylase (HPA) and alpha-glucosidase (HLAG) with IC50 values of 28.35 µM and 26.21 µM, respectively. It enhances glucose uptake in L6 myotubes and improves glucose homeostasis, insulin sensitivity, and lipid metabolism in a rat model of Streptozotocin-induced diabetes.
Molecular Weight:
436.51
Formula:
C21H16N4O3S2
Target:
PPAR
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