NEK7-IN-2 (compound 23) is a potent inhibitor of the NLRP3-NEK7 interaction. It enhances the thermal stability of NEK7 and modulates the assembly of the NLRP3 inflammasome. Additionally, NEK7-IN-2 inhibits the release of IL-1beta.
Molecular Weight:
544.54
Formula:
C27H28F4N6O2
Target:
Others|||MAPK
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