GC-072 is a potent 4-oxoquinolizine antibiotic that selectively inhibits bacterial topoisomerase. It shows in vitro activity against both sensitive and resistant strains of B. pseudomallei, and it is also effective against other dangerous pathogens such as Burkholderia mallei, Bacillus anthracis, Yersinia pestis, and Francisella tularensis. In a murine model of melioidosis, oral administration of GC-072 demonstrated dose-dependent survival benefits, indicating its potential as a first-line oral treatment option for melioidosis.
Molecular Weight:
370.35
CAS Number:
[1371629-36-5]
Formula:
C20H16F2N2O3
Target:
Others
T203732
* VAT and and shipping costs not included. Errors and price changes excepted
