BGC4 is a gold(III) complex based on biphenyl. It inhibits human recombinant thioredoxin reductase (TrxR) with an IC50 of 10.7 µM, exhibits cytotoxicity with an IC50 of 5.4 µM in MDA-MB-231 cells, and induces apoptosis. Additionally, BGC4 demonstrates antitumor activity in mouse models.
Molecular Weight:
724.01
Formula:
C30H32AuClF3N3
Target:
Apoptosis
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