PFK-IN-1 (compound 1) is an inhibitor of 6-phosphofructo-1-kinase (PFK), demonstrating IC50 values of 0.41 and 0.23 µM against T. brucei and T. cruzi PFK, respectively, and an ED50 of 15.18 µg/mL for T. brucei. The compound has a half-life of 9.7 minutes in rat liver microsomes and 408 minutes in mouse liver microsomes.
Molecular Weight:
440.3
CAS Number:
[735303-62-5]
Formula:
C18H15Cl2N3O4S
Target:
Parasite
T204311
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