TMX-2138 is a CDKs PROTAC degrader, with IC50 values of 8.7 nM for CDK1/cyclinB, 10.9 nM for CDK2/cyclinA, 7.0 nM for CDK5/p25, and 25.7 nM for CDK9/cyclinT1. It enhances the ubiquitination and degradation of CDKs and is utilized for ovarian cancer research.
Molecular Weight:
956.791
CAS Number:
[2488892-07-3]
Formula:
C40H43BrFN9O11S
Target:
CDK|||PROTACs
T204343
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