JAK-IN-39 (compound 11) is a JAK inhibitor with IC50 values of 0.05 nM for JAK1, 1.18 nM for JAK2, and 0.03 nM for JAK3. It reduces cell viability in TF-1 cells and inhibits the production of TNFalpha and INFgamma in lymphocytes in vitro.
Molecular Weight:
498.54
CAS Number:
[2250013-34-2]
Formula:
C25H26N10O2
Target:
TNF|||JAK
T204364
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