ERBB agonist-1 (Compound EF-1) is an ERBB4 agonist (EC50=10.5 µM) that induces ERBB4 receptor dimerization and phosphorylation of Akt and ERK1/2. It exhibits cardioprotective effects in mouse models and prevents myocardial fibrosis.
Molecular Weight:
419.54
Purity:
99.90%
CAS Number:
[930856-19-2]
Formula:
C24H25N3O2S
Target:
ERK|||EGFR|||Akt
T204401
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