ATIC-IN-2 (Compound 1) is a competitive inhibitor of the bifunctional enzyme AICAR transformylase/IMP cyclohydrolase (ATIC) that binds to the inosine monophosphate cyclohydrolase (IMPCH) domain with a Ki value of 0.13 µM, ATIC-IN-2 is commonly employed in purine biosynthesis research to dissect nucleotide metabolism, enzyme regulation, and metabolic vulnerabilities in cancer cells.
Molecular Weight:
188.17
CAS Number:
[67095-44-7]
Formula:
C4H4N4O3S
Target:
DNA/RNA Synthesis|||Others
T204433
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