FW-1 is a type I inhibitor of FLT3, with an IC50 of approximately 1 µM. It exhibits cytotoxic effects in FLT3-mutant AML cells, causes cell cycle arrest at the G0/G1 phase, and induces apoptosis in MV4-11 and MOLM-13 cells.
Molecular Weight:
429.517
CAS Number:
[3094389-92-8]
Formula:
C24H27N7O
Target:
FLT|||Apoptosis
T204464
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