MLK3-IN-1 (Compound 37) is a selective inhibitor of mixed-lineage kinase 3 (MLK3) with an IC50 of less than 1 nM. It also inhibits FAK with an IC50 of 15.5 µM. In both murine and human liver microsomes, MLK3-IN-1 demonstrates excellent metabolic stability.
Molecular Weight:
490.422
Formula:
C20H16F6N4O2S
Target:
MLK|||FAK
T204487
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