MTHFD2-IN-5 (Compound 16e) is a selective inhibitor of MTHFD2 with an IC50 of 66 nM. It inhibits the proliferation of MOLM-14 cells with a GI50 of 720 nM and demonstrates antitumor activity in mouse models.
Molecular Weight:
467.821
Formula:
C17H18ClN7O7
Target:
Dehydrogenase
T204594
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