CD73-IN-19 (Compound 4ab) is an inhibitor of CD73, demonstrating a 44% inhibition rate of CD73 enzyme activity at 100 µM. It entirely counters T cell proliferation blockade triggered by TCR activation (induced by CD73 activity) at 10 µM and 100 µM and inhibits hA2A receptor activity in HEK-293 cells with a Ki of 3.31 µM. CD73-IN-19 holds potential for research in the field of immune diseases.
Molecular Weight:
355.411
CAS Number:
[333329-22-9]
Formula:
C18H17N3O3S
Target:
CD73
T204632
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