iHAC is an inhibitor-HSP90 anchoring chimera that covalently binds to the BRD4 ligand (+)-JQ-1, targeting HSP90 and thereby inhibiting cancer cell proliferation. This compound also triggers an anti-tumor immune response and is effective in suppressing the recurrence and metastasis of 4T1 breast cancer in mouse models.
Molecular Weight:
1241.56
Formula:
C50H46ClIN16O7S3
Target:
Epigenetic Reader Domain
T204715
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