Tamoxifen-PEG-Clozapine is an estrogen receptor alpha (ERalpha) PROTAC degrader. It targets ERalpha for degradation through the ubiquitin-proteasome system by utilizing the E3 ubiquitin ligase component N-recognin 5. This compound is applicable in cancer research. (Pink: ERalpha inhibitor, Black: linker, Blue: CRBN Ligand)
Molecular Weight:
943.567
Formula:
C54H63ClN6O7
Target:
Estrogen Receptor/ERR|||PROTACs
T204719
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