JH-FK-08 is an inhibitor of the serine/threonine-specific phosphatase enzyme calcineurin (calcium-dependent phosphatase). It demonstrates antifungal activity, effectively inhibiting C. neoformans with a MIC80 of 0.8 µg/mL. Additionally, JH-FK-08 exhibits immunosuppressive properties by inhibiting IL-2 expression with an IC50 of 42.6 nM, and shows anti-infective activity in mouse models.
Molecular Weight:
864.073
Formula:
C45H73N3O13
Target:
Antifungal|||Interleukin
T204721
* VAT and and shipping costs not included. Errors and price changes excepted
