GHP-88309 is an orally active, broad-spectrum anti-paramyxovirus agent that targets viral polymerase, interrupting viral RNA synthesis. It effectively inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with an EC50 of 0.06-1.2 µM. In mouse models, GHP-88309 demonstrates significant anti-infective activity.
Molecular Weight:
266.27
CAS Number:
[1269267-87-9]
Formula:
C16H11FN2O
Target:
RSV|||DNA/RNA Synthesis
T204819
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