MurA-IN-5 (compound 4c) demonstrates a minimum inhibitory concentration (MIC) of 1.95 µg/mL against Escherichia coli and exhibits significant potency as a MurA inhibitor with an IC50 of 3.77 µg/mL. It also shows antibiofilm activity against various microorganisms, indicating its potential in combating biofilm-related infections.
Molecular Weight:
540.614
Formula:
C33H28N6O2
Target:
Antibacterial
T204931
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