D-PheTrAP is a bisubstrate analog inhibitor of 1-deoxy-d-xylulose 5-phosphate synthase (DXPS). It inhibits Escherichia coli DXPS (EcDXPS) and Pseudomonas aeruginosa DXPS (PaDXPS) with IC50 values of 0.52 µM, 2.1 µM, 2.4 µM, and 1.7 µM for wild-type (WT) EcDXPS, EcA426E, WT PaDXPS, and PaE431A, respectively.
Molecular Weight:
367.294
CAS Number:
[2241298-26-8]
Formula:
C15H18N3O6P
Target:
Antibacterial
T204969
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