V-161 is an orally active Na+-V-ATPase inhibitor with an IC50 of 144 nM. Under alkaline conditions, V-161 inhibits Enterococcus hirae and vancomycin-resistant Enterococcus faecium (VRE), with MIC values of 4 µg/mL for both. Additionally, V-161 can inhibit the colonization of VRE in the mouse small intestine.
Molecular Weight:
251.326
CAS Number:
[69570-95-2]
Formula:
C16H17N3
Target:
ATPase|||Antibacterial
T204979
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