TrxR1-IN-2 (Compound 6a) acts as a TrxR1 inhibitor that covalently bonds with the Cys475 and Sec498 sites of TrxR1. This interaction hampers TrxR1 activity, resulting in a redox homeostasis disruption and inducing apoptosis and ferroptosis.
Molecular Weight:
361.389
Formula:
C19H23NO6
Target:
Apoptosis|||Ferroptosis
T204985
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