Topoisomerase I/II inhibitor 8, CAS [[355400-87-2]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T204994
Supplier Catalog Number:
T204994
Alternative Catalog Number:
TGM-T204994-10MG,TGM-T204994-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
TopoisomeraseI/II inhibitor 8 (Compound Ru7) is a dual catalytic inhibitor of TopoisomeraseI/II that induces DNA damage and activates PARP-1, leading to the activation of RIPK1, RIPK3, and MLKL, ultimately causing necroptosis. It shows significant anticancer activity by effectively targeting cancer cell nuclei and inducing cell death through necroptosis, offering substantial clinical potential in overcoming resistance in cancer treatment.
