ARN23765 is an F508del-CFTR corrector with an EC50 of 38 pM in human bronchial epithelial cells. It enhances the maturation and function of F508del-CFTR at the cell membrane, influencing ion transport and secretion, thereby addressing the pathological mechanisms of cystic fibrosis (CF).
Molecular Weight:
615.504
CAS Number:
[2244458-40-8]
Formula:
C30H22F5N3O6
Target:
CFTR
T205032
* VAT and and shipping costs not included. Errors and price changes excepted
