KRAS inhibitor-27, CAS [[3033690-83-1]] Preis auf Anfrage

Product Overview

• Article Name: KRAS inhibitor-27, CAS [[3033690-83-1]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T205081
• Supplier Catalog Number: T205081
• Alternative Catalog Number: TGM-T205081-10MG,TGM-T205081-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

KRAS inhibitor-27 (Compound 15h) is a KRAS inhibitor that effectively targets KRAS G12D/G12V mutated cells (AsPC-1 and SW620) and wild-type KRAS cells (HT-29), with IC50 values of 378 nM, 0.6 nM, and 3230 nM, respectively. It reduces ERK phosphorylation, with IC50 values of 0.6 nM and 1 nM in AsPC-1 and SW620 cells, respectively, and decreases DUSP4 expression, thereby inhibiting the MAPK signaling pathway.

Product Properties

• Molecular Weight: 657.106
• CAS Number: [3033690-83-1]
• Formula: C31H28ClF3N6O3S
• Target: ERK|||Ras|||p38 MAPK

Images

T205081