PROTAC CG167 is a potent and selective PROTAC degrader of CypA. It degrades CypA in a dose-dependent manner in Jurkat cells, with a DC50 of 123 nM. Additionally, PROTAC CG167 exhibits antiviral activity by inhibiting HIV-1 and HCV. (Pink: CypA Ligand, Black: Linker, Blue: E3LigaseLigand)
Molecular Weight:
1250.47
Formula:
C65H79N13O11S
Target:
HIV Protease|||HCV Protease|||PROTACs
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