ErSO-TFPy activates the sodium ion channel TRPM4, resulting in an imbalance of intracellular calcium and sodium ions. It exhibits low nanomolar-level cytotoxicity (IC50 = 5-25 nM) by inducing necrosis in ERalpha+ breast cancer cell lines. Additionally, ErSO-TFPy shows antitumor activity in mouse models.
Molecular Weight:
434.307
CAS Number:
[3035547-78-2]
Formula:
C19H13F7N2O2
Target:
Sodium Channel
T205320
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