ATG16L1 stabilizer-1 (compound A3B) is an FKBP12-independent stabilizer of ATG16L1 that enhances cellular autophagy (Autophagy). Regardless of the presence of FKBP12, it has an inhibitory EC50 value of 12.1 µM for ATG16L1. When used alone, ATG16L1 stabilizer-1 can induce GFP-LC3 puncta formation, with an EC50 value of 12.0 µM.
Molecular Weight:
911.13
Formula:
C45H62N14O5S
Target:
Autophagy
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