PD-L1/VISTA-IN-2 (Compound S8) is an orally active dual inhibitor targeting PD-L1 and VISTA, with an IC50 of 1.4 µM for PD-L1 and a KD of 2.1 µM for VISTA. This compound can activate the tumor immune microenvironment, exerting anticancer effects.
Molecular Weight:
362.42
Formula:
C22H22N2O3
Target:
PD-1/PD-L1
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