13-TP is an inhibitor of SARS-CoV-2. It effectively suppresses in vitro RNA synthesis catalyzed by the central replication-transcription complex (C-RTC, nsp12-nsp7-nsp82) of SARS-CoV-2. 13-TP fully inhibits RdRp polymerase activity and obstructs the complete extension of some primer RNAs.
Molecular Weight:
570.23
Formula:
C12H19F2N6O12P3
Target:
DNA/RNA Synthesis|||SARS-CoV
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