TrxR/EGFR-IN-1, CAS [[3038386-42-1]] Preis auf Anfrage
Biozol Catalog Number:
TGM-T205519
Supplier Catalog Number:
T205519
Alternative Catalog Number:
TGM-T205519-10MG,TGM-T205519-50MG
Manufacturer:
TargetMol
Category:
Biochemikalien
TrxR/EGFR-IN-1 (Compound L1Au2) is a TrxR/EGFR inhibitor with activity against both gefitinib-sensitive and -resistant lung cancer, effectively suppressing tumor proliferation and promoting apoptosis. It enhances GPX4 degradation through autophagosome-lysosome and proteasome pathways, leading to ferroptosis. Additionally, it induces endoplasmic reticulum stress and triggers immunogenic cell death, making it applicable for studies on gefitinib-resistant lung cancer.
Molecular Weight:
710.878
CAS Number:
[3038386-42-1]
Formula:
C24H24AuClFN6O2P
Target:
Apoptosis|||EGFR|||Ferroptosis
T205519
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