OA-Br-1 is an orally active, selective inhibitor of PTP1B with an IC50 value of 7.08 µM. It induces apoptosis and exhibits broad-spectrum anti-cancer cell proliferation activity. OA-Br-1 exerts anti-breast cancer effects both in vitro and in vivo through the PTP1B/PI3K/AKT signaling pathway.
Molecular Weight:
808.92
Formula:
C43H70BrNO8
Target:
Apoptosis|||Phosphatase
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