DBCO-PEG4-VC-PAB-MMAD is a click-reactive Drug-linker that contains a DBCO group and can undergo a strain-promoted acetylene-nitride cycloaddition reaction (SPAAC) with molecules containing an Azide group. MMAD is an effective microtubule (tubulin) inhibitor. DBCO-PEG4-VC-PAB-MMAF, DBCO-PEG4-VC-PAB-MMAD can be used in the synthesis of antibody-drug conjugates (ADC).
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