Nitric oxide production-IN-2, CAS [[1019984-44-1]] Preis auf Anfrage

Product Overview

• Article Name: Nitric oxide production-IN-2, CAS [[1019984-44-1]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T206206
• Supplier Catalog Number: T206206
• Alternative Catalog Number: TGM-T206206-10MG,TGM-T206206-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

TLR4/JNK/NF-kappaB-IN-1 (Racemic-11k) is an inhibitor of TLR4, JNK, and NF-kappaB. It suppresses NO production in LPS-stimulated RAW264.7 cells with an IC50 of 23.2 µM. By inhibiting TLR4 expression and reducing JNK phosphorylation, TLR4/JNK/NF-kappaB-IN-1 prevents NF-kappaB activation. This leads to a decrease in the transcription of inflammation-related genes, reducing the expression of iNOS and COX-2, and the production of inflammatory mediators such as NO, PGE2, and TNF-alpha, thereby exhibiting anti-inflammatory activity. TLR4/JNK/NF-kappaB-IN-1 holds potential in the study of inflammatory diseases, including rheumatoid arthritis and various other inflammatory conditions.

Product Properties

• Molecular Weight: 344.403
• CAS Number: [1019984-44-1]
• Formula: C23H20O3
• Target: NF-kappaB|||JNK|||TLR

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T206206