AB-3PRGD2 is a radiolabeled agent that targets integrin alphavbeta3. It enhances tumor uptake and prolongs retention time in tumors, significantly improving the inhibition of tumor growth. AB-3PRGD2 also remodels the tumor immune microenvironment by upregulating PD-L1 expression and increasing tumor-infiltrating CD8+ T cells.
Molecular Weight:
3161.32
CAS Number:
[2416165-76-7]
Formula:
C137H215IN30O45S
Target:
PD-1/PD-L1|||Integrin
T206427
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