Antitumor agent-200, CAS [[3046118-64-0]] Preis auf Anfrage

Product Overview

• Article Name: Antitumor agent-200, CAS [[3046118-64-0]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T206452
• Supplier Catalog Number: T206452
• Alternative Catalog Number: TGM-T206452-10MG,TGM-T206452-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

Antitumor agent-200 (Compound 2g) is a microtubule synthesis inhibitor that binds to the colchicine site on tubulin, causing G2/M cell cycle arrest and inducing reactive oxygen species (ROS) production. It demonstrates significant inhibitory activity against P-glycoprotein (P-gp) overexpressing cell lines MCF7/ADR and KBV200, with resistance indices (DRI) of 0.83 and 0.58, respectively. In an MCF-7 xenograft model, Antitumor agent-200 (at 25 mg/kg, administered intraperitoneally) achieves a 57.2% tumor growth inhibition rate. This compound is applicable for research in the field of cancer therapy.

Product Properties

• Molecular Weight: 423.34
• CAS Number: [3046118-64-0]
• Formula: C19H21FN2O3Se
• Target: P-gp|||Microtubule Associated

Images

T206452