Microtubulin-IN-1, CAS [[3025180-14-4]] Preis auf Anfrage

Catalog Number: TGM-T206493
Article Name: Microtubulin-IN-1, CAS [[3025180-14-4]] Preis auf Anfrage
Biozol Catalog Number: TGM-T206493
Supplier Catalog Number: T206493
Alternative Catalog Number: TGM-T206493-10MG,TGM-T206493-50MG
Manufacturer: TargetMol
Category: Biochemikalien
Microtubulin-IN-1 (Compound 8g) is an inhibitor of microtubulin, targeting the colchicine-binding site to disrupt tubulin integrity and induce upregulation of p53 protein expression. It exhibits antiproliferative activity across various cancer cell lines, including NCI-H460, BxPC-3, and HT-29, with IC50 values of 2.4, 1.6, and 2.07 nM, respectively. Additionally, Microtubulin-IN-1 induces cell cycle arrest at the G2/M phase and apoptosis in NCI-H460 cells.
Molecular Weight: 444.458
CAS Number: [3025180-14-4]
Formula: C25H21FN4O3
Target: Apoptosis|||MDM-2/p53|||Microtubule Associated
T206493