R1-ICR-5, CAS [[3070346-91-4]] Preis auf Anfrage

Product Overview

• Article Name: R1-ICR-5, CAS [[3070346-91-4]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T206654
• Supplier Catalog Number: T206654
• Alternative Catalog Number: TGM-T206654-10MG,TGM-T206654-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

R1-ICR-5 is a selective PROTAC degrader targeting serine/threonine-protein kinase 1 (RIPK1). Mediated by VHL, R1-ICR-5 promotes the degradation of RIPK1, disrupting the TNFR1 and TLR3/4 signaling hubs, enhancing NF-kappaB, MAPK, and IFN signal output, and facilitating RIPK3 activation and necroptosis induction. R1-ICR-5 holds potential for research in cancer and inflammatory diseases.

Product Properties

• Molecular Weight: 1007.31
• CAS Number: [3070346-91-4]
• Formula: C54H70N8O7S2
• Target: Serine/threonin kinase|||p38 MAPK|||NF-kappaB|||PROTACs|||TLR|||TNF

Images

T206654