Ferroptosisinducer-7 is an orally active and selective inducer of ferroptosis, operating through the inositol 1,4,5-trisphosphate receptor (IP3R)/ORAI calcium release-activated calcium channel protein. This compound significantly alleviates anemia, inhibits bone marrow CTL activation, and improves hematopoietic function in immune-mediated bone marrow failure. It is utilized in research on aplastic anemia.
Target:
Ferroptosis|||ERK|||p38 MAPK|||MEK
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