PRMT5-IN-50, CAS [[3002409-47-1]] Preis auf Anfrage

Product Overview

• Article Name: PRMT5-IN-50, CAS [[3002409-47-1]] Preis auf Anfrage
• Biozol Catalog Number: TGM-T206754
• Supplier Catalog Number: T206754
• Alternative Catalog Number: TGM-T206754-10MG, TGM-T206754-50MG
• Manufacturer: TargetMol
• Category: Biochemikalien

Product Description

PRMT5-IN-50 is an orally active selective inhibitor of PRMT5, demonstrating good metabolic stability and low clearance in human liver microsomes. It inhibits SDMA/HCT116-MTAPdel and SDMA/HCT116-MTAPwt with IC50 values for symmetric arginine methylation inhibition at 1.0 and 536 nM, respectively, and antiproliferative IC50 values at 19 and 1620 nM, respectively. Additionally, PRMT5-IN-50 suppresses tumor growth in mice.

Product Properties

• Molecular Weight: 492.496
• CAS Number: [3002409-47-1]
• Formula: C26H23F3N6O
• Target: Histone Methyltransferase

Images

T206754